Find out if their COPD is genetic by screening for alpha1-antitrypsin (AAT) deficiency

AlphaID™ offers fast, free, and accurate ways to screen patients for alpha-1. By screening, you can help ensure patients receive an accurate diagnosis and the right treatment plan.*

AlphaID Cheek Swab

Healthcare providers can use the AlphaID cheek swab to screen patients with COPD or treatment-resistant asthma for alpha-1.

AlphaID CONFIRM

Healthcare providers can use AlphaID CONFIRMTM, a simple fingerstick, to test for or confirm an alpha-1 diagnosis.

AlphaID at Home

Patients can use the AlphaIDTM at Home cheek swab on their own to screen for alpha-1 by ordering a free kit.

Learn About AlphaID Screening Kits

*The receipt of these free testing services does not create any expectation or obligation to purchase or use any product or service offered by any manufacturer.

>90% of patients with AAT deficiency are undiagnosed1

AAT deficiency, also called alpha-1 or genetic COPD, is a relatively common but widely underrecognized inherited condition that increases the risk of early-onset COPD.2-4 Alpha-1 may be a contributing cause in up to 3% of COPD cases in the United States.3,5

Learn About AAT Deficiency

Follow the screening guidelines

Major respiratory organizations recommend screening for alpha-1 in all of your patients with COPD or treatment-resistant asthma.2,6-9

Learn more about the Alpha-1 Screening Guidelines

Is AAT deficiency behind their COPD?

Primary care providers and other allied healthcare providers are likely to be the first point of contact for patients with COPD.2 Your role is vital to increasing identification and diagnosis of AAT deficiency, an inherited, potentially fatal condition.2-4 Genetic testing is required to detect and diagnose AAT deficiency.5

Watch a pulmonologist discuss the importance of screening all of your patients with COPD or treatment-resistant asthma for AAT deficiency.

Order Free AlphaID Test Kits
AlphaID genetic screening test that detects the 14 most prevalent alleles associated with AAT deficiency

AlphaID makes screening fast, free, and accurate*

AlphaID is an advanced genetic screening test that detects the 14 most prevalent alleles associated with AAT deficiency.10

Order Free AlphaID Test Kits

Up Next: Alpha-1 & COPD

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COPD, chronic obstructive pulmonary disease.
AAT, alpha-1 antitrypsin.

References:

  1. Brantly M, Campos M, Davis AM, et al. Detection of alpha-1 antitrypsin deficiency: The past, present and future. Orphanet J Rare Dis. 2020;15(1):96. doi:10.1186/s13023-020-01352-5
  2. Campos MA, Wanner A, Zhang G. Snadhaus RA. Trends in the diagnosis of symptomatic patients with a1-antitrypsin deficiency between 1968 and 2003. CHEST. 2005;128(3):1179-1186.
  3. Stoller JK. Myths and misconceptions about a1-antitrypsin deficiency. Arch Intern Med. 2009; 169(6): 546-550.
  4. Stoller JK, Aboussouan LS. A review of alpha-1 antitrypsin deficiency. Am J Respir Crit Care Med. 2012;185(3): 246-259.
  5. Testing & diagnosis - alpha-1 foundation. Alpha-1 Foundation. September 11, 2023. Accessed June 3, 2024. https://alpha1.org/about-alpha-1-testing-diagnosis/.
  6. Sandhaus RA, Turino G, Brantly ML, et al. The diagnosis and management of alpha-1 antitrypsin deficiency in the adult. Chronic Obstr Pulm Dis. 2016; 3(3):668-682.
  7. American Thoracic Society/European Respiratory Society. American Thoracic Society/European Respiratory Society statement: standards for the diagnosis and management of individuals with alpha-1 antitrypsin deficiency. Am J Respir Crit Care Med.  2003:168(7): 818-900.
  8. 2024 Gold Report - Global Initiative for Chronic Obstructive Lung Disease. GOLD. November 12, 2023. Accessed May 2, 2024. https://goldcopd.org/2024-gold-report/.
  9. World Health Organization. Alpha 1-antitrypsin deficiency memorandum from WHO meeting. Bull World Health Org. 1997;75(5):397-415.
  10. A1AT Genotyping Test package insert. Progenika Biopharma.