home-2

~90% of patients with alpha-1 are undiagnosed2,3

Alpha1-antitrypsin (AAT) deficiency, also known as alpha-1 or genetic COPD, is one of the world's most prevalent, potentially fatal hereditary diseases.3,4
Alpha-1 may be a contributing cause for up to 3% of all COPD cases in the United States.1,3

Learn more about alpha-1 >

Home screening

Screening for alpha-1 is free,* fast, and easy with AlphaID

AlphaID is a fast and easy cheek swab that screens for alpha-1.5 Ruling out alpha-1 as a contributing cause of COPD has never been easier.

Order free AlphaID kits now >

Home Leading

Leading clinical organizations recommend screening all patients with COPD for alpha-16-10

Screening of all patients with COPD for alpha-1, regardless of age and smoking history, is recommended by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) and the World Health Organization (WHO), as well as the following organizations

Home 3 logos

American Thoracic Society (ATS)

American College of Chest Physicians

COPD Foundation

home link

Learn more about clinical guidelines >

Home band

 

*AlphaID is completely free, provided compliments of Grifols, and may not be billed to patients or their insurers.

Order free AlphaID™ screening kits

Home references

COPD, chronic obstructive pulmonary disease.


References: 
  1. Alpha-1 Foundation. Lung disease. https://www.alpha1.org/Newly-Diagnosed/Learning-about-Alpha-1/Lung-Disease. Accessed October 28, 2019.
  2. Alpha-1 Foundation. Look into genetic COPD. https://www.alpha1.org/Alphas-Friends-Family/Resources/News/ArtMID/5952/ArticleID/7792/Grifols-launches-educational-campaign-Look-into-Genetic-COPD. Published February 28, 2018. Accessed November 4, 2019.
  3. Campos MA, Wanner A, Zhang G, Sandhaus RA. Trends in the diagnosis of symptomatic patients with α1-antitrypsin deficiency between 1968 and 2003. J Clin Invest. 1999;104(3):337-344.
  4. Campbell EJ, Campbell MA, Boukedes SS, Owen CA. Quantum proteolysis by neutrophils: implications for pulmonary emphysema in α1-antitrypsin deficiency. J Clin Invest. 1999;104(3):337-344.
  5. A1AT Genotyping Test Package Insert. Progenika Biopharma.
  6. Global Initiative for Chronic Obstructive Lung Disease. Pocket guide to COPD diagnosis, management, and prevention. https://goldcopd.org/wp-content/uploads/2018/11/GOLD-2019-POCKET-GUIDE-DRAFT-v1.7-14Nov2018-WMS.pdf. Accessed November 7, 2019.
  7. World Health Organization. α1-antitrypsin deficiency: memorandum from a WHO meeting. Bull World Health Organ. 1997;75(5):397-415.
  8. American Thoracic Society/European Respiratory Society. American Thoracic Society/European Respiratory Society statement: standards for the diagnosis and management of individuals with alpha-1 antitrypsin deficiency. Am J Respir Crit Care Med. 2003;168(7):818-900.
  9. CHEST Foundation. Learn about alpha-1 antitrypsin deficiency. https://foundation.chestnet.org/patient-education-resources/alpha-1-antitrypsin-deficiency/. Accessed November 3, 2019.
  10. Sandhaus RA, Turino G, Brantly ML, et al. The diagnosis and management of alpha-1 antitrypsin deficiency in the adult. Chronic Obstr Pulm Dis. 2016;3(3):668-682.